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Tsuguhito Ota Selected Research

astaxanthine (astaxanthin)

1/2021Prevention of NAFLD/NASH by Astaxanthin and β-Cryptoxanthin.
5/2018Protective effects of astaxanthin on a combination of D-galactose and jet lag-induced aging model in mice.
10/2017β-Cryptoxanthin exerts greater cardioprotective effects on cardiac ischemia-reperfusion injury than astaxanthin by attenuating mitochondrial dysfunction in mice.
4/2017Nonalcoholic Fatty Liver Disease and Insulin Resistance: New Insights and Potential New Treatments.
3/2017Hepatic Transcriptome Profiles of Mice with Diet-Induced Nonalcoholic Steatohepatitis Treated with Astaxanthin and Vitamin E.
1/2017Reply to the Letter to the Editor by Li et al.: Bioinformatics Analysis in Mice with Diet-Induced Nonalcoholic Steatohepatitis Treated with Astaxanthin and Vitamin E.
8/2016Micronutrient Antioxidants and Nonalcoholic Fatty Liver Disease.
6/2016Novel Action of Carotenoids on Non-Alcoholic Fatty Liver Disease: Macrophage Polarization and Liver Homeostasis.
11/2015Astaxanthin prevents and reverses diet-induced insulin resistance and steatohepatitis in mice: A comparison with vitamin E.

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Tsuguhito Ota Research Topics

Disease

45Insulin Resistance
01/2021 - 11/2006
30Inflammation (Inflammations)
12/2021 - 11/2007
27Non-alcoholic Fatty Liver Disease
12/2021 - 03/2007
19Obesity
01/2021 - 11/2006
15Fibrosis (Cirrhosis)
01/2021 - 01/2007
14Type 2 Diabetes Mellitus (MODY)
01/2021 - 03/2007
12Fatty Liver
12/2021 - 01/2007
4Weight Gain
12/2021 - 01/2017
3Weight Loss (Weight Reduction)
01/2020 - 06/2017
3Glucose Intolerance
11/2019 - 07/2012
3Endotoxemia
09/2019 - 01/2017
3Liver Diseases (Liver Disease)
01/2018 - 01/2014
3Type 1 Diabetes Mellitus (Autoimmune Diabetes)
01/2005 - 06/2003
2Disease Progression
01/2021 - 04/2017
2Hyperinsulinism (Hyperinsulinemia)
11/2020 - 11/2019
2Liver Neoplasms (Liver Cancer)
01/2020 - 12/2017
2Mitochondrial Diseases (Mitochondrial Disease)
11/2019 - 10/2017
2Hypoxia (Hypoxemia)
10/2019 - 10/2018
2Diabetic Nephropathies (Diabetic Nephropathy)
10/2019 - 08/2005
2Albuminuria
10/2018 - 08/2005
2Neoplasms (Cancer)
03/2018 - 12/2017
2Body Weight (Weight, Body)
01/2018 - 01/2012
2Hepatocellular Carcinoma (Hepatoma)
12/2017 - 03/2013
1Alzheimer Disease (Alzheimer's Disease)
11/2020
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2020
1Gout
01/2020
1Hyperuricemia
01/2020
1Chronic Renal Insufficiency
10/2019
1Infections
09/2019
1Sinusitis
06/2019
1Systemic Vasculitis
06/2019
1Rhinorrhea
06/2019
1Meningitis
06/2019

Drug/Important Bio-Agent (IBA)

21Glucose (Dextrose)FDA LinkGeneric
01/2021 - 03/2007
18LipidsIBA
01/2021 - 11/2007
9astaxanthine (astaxanthin)IBA
01/2021 - 11/2015
8Reactive Oxygen Species (Oxygen Radicals)IBA
11/2019 - 07/2008
8Proteins (Proteins, Gene)FDA Link
10/2019 - 11/2010
7CholesterolIBA
12/2021 - 11/2007
7Insulin (Novolin)FDA Link
11/2020 - 11/2003
7AntioxidantsIBA
11/2019 - 11/2007
6CryptoxanthinsIBA
01/2021 - 01/2014
5LigandsIBA
12/2021 - 07/2012
5ChemokinesIBA
12/2021 - 06/2013
5EnzymesIBA
01/2020 - 06/2003
5Fatty Acids (Saturated Fatty Acids)IBA
01/2020 - 11/2007
5Vitamin EFDA LinkGeneric
01/2019 - 11/2015
5MicronutrientsIBA
01/2019 - 06/2016
4CC ChemokinesIBA
12/2021 - 04/2013
4Carotenoids (Carotene)IBA
11/2019 - 03/2015
4Sodium-Glucose Transporter 2 InhibitorsIBA
10/2019 - 06/2017
4Triglycerides (Triacylglycerol)IBA
08/2017 - 01/2007
4Chemokine ReceptorsIBA
07/2015 - 07/2012
3Choline (Choline Chloride)IBA
10/2020 - 01/2007
3glucoraphaninIBA
11/2019 - 01/2017
3Plasminogen Activator Inhibitor 1IBA
10/2019 - 11/2006
3empagliflozinIBA
01/2019 - 06/2017
3Sodium-Glucose Transport ProteinsIBA
01/2019 - 06/2017
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2018 - 11/2006
3Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
07/2015 - 04/2013
3Selenoprotein PIBA
09/2014 - 11/2010
3Pioglitazone (Actos)FDA Link
12/2010 - 01/2007
2Messenger RNA (mRNA)IBA
12/2021 - 11/2010
2Chemotactic FactorsIBA
12/2021 - 05/2014
2LeptinIBA
12/2021 - 01/2021
2CytokinesIBA
01/2021 - 07/2015
2AdiponectinIBA
01/2021 - 01/2012
2LycopeneIBA
01/2020 - 11/2019
2Transforming Growth Factors (Transforming Growth Factor)IBA
01/2020 - 03/2018
2Hypoglycemic Agents (Hypoglycemics)IBA
01/2020 - 03/2007
2Alanine Transaminase (SGPT)IBA
01/2020 - 01/2018
2Glucagon (Glukagon)FDA Link
10/2019 - 03/2007
2AMP-Activated Protein KinasesIBA
10/2019 - 01/2018
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2019 - 09/2014
21,5- anhydro- 1- (5- (4- ethoxybenzyl)- 2- methoxy- 4- methylphenyl)- 1- thioglucitolIBA
10/2019 - 10/2018
2LipopolysaccharidesIBA
09/2019 - 01/2018
2Sitagliptin Phosphate (Januvia)FDA Link
01/2018 - 10/2016
2sulforaphaneIBA
01/2018 - 01/2017
2Nonesterified Fatty Acids (NEFA)IBA
01/2018 - 05/2009
2Phosphotransferases (Kinase)IBA
01/2018 - 03/2013
2Pharmaceutical PreparationsIBA
12/2010 - 07/2008
2Methionine (L-Methionine)FDA Link
07/2008 - 01/2007
2ProcollagenIBA
07/2008 - 07/2008
2tranilastIBA
07/2008 - 08/2005
1Phospholipids (Phosphatides)FDA LinkGeneric
11/2020
1heat-shock protein 70.1IBA
11/2020
1Hydroxyproline (4 Hydroxyproline)IBA
11/2020
1anagliptinIBA
10/2020
1Amino AcidsFDA Link
10/2020
1FebuxostatFDA Link
01/2020
1Allopurinol (Remid)FDA LinkGeneric
01/2020
1Xanthine OxidaseIBA
01/2020
1Aspartate Aminotransferases (Aspartate Transaminase)IBA
01/2020
1Biomarkers (Surrogate Marker)IBA
01/2020
1pimonidazoleIBA
10/2019
1AICA ribonucleotide (ZMP)IBA
10/2019
1Oxygen (Dioxygen)IBA
10/2019
1Coloring Agents (Dyes)IBA
10/2019

Therapy/Procedure

5Therapeutics
01/2021 - 06/2016
2Transplantation
01/2021 - 07/2012